Biomap explore measurable predictors (biomarkers) linked with negative health complications in psoriasis

In a recent paper published in the British Journal of Dermatology, the Biomap consortium performed a scoping review of biomarker studies investigating disease progression in psoriasis.


What are biomarkers?
According to the Biomap consortium “Biomarkers are molecules that naturally exist within the human body and are often present at different levels in people who do not respond well to particular a treatment.”

What is psoriasis?
Psoriasis is a common inflammatory skin condition affecting up to 2% of the Irish population. It is characterised by red raised patches which can be sometimes covered with a silvery white scale, also known as plaques. These plaques can vary in size on the skin, and may be dry, itchy, and sometimes flake. Psoriasis can start at any time of life and affects males and females equally.

There are two peak ages of occurrences 16-22 years, and 55-60 years, and may present earlier in women.

Related: The ISF psoriasis information webpage
Related: The ISF booklet what you need to know about psoriasis.
Related: Biomap project

What other health conditions are associated with psoriasis?
There are a number of other health conditions (often called comorbidities) that have been associated with psoriasis, particularly psoriatic arthritis. Psoriatic arthritis is a form of arthritis that affects some people living with psoriasis and may cause affected joints to become painful, stiff and swollen.

Other health conditions associated with psoriasis include type 2 diabetes, high blood pressure, high cholesterol, cardiovascular disease (heart attack, stroke), and to be above a healthy weight. Psoriasis is also linked with a higher risk of anxiety and depression. If you have psoriasis, ask your doctor about your risk for heart disease, type 2 diabetes, high cholesterol, and high blood pressure. If you have symptoms of arthritis, you may be referred to a rheumatologist who is a specialist consultant doctor that can diagnose and treat forms of arthritis.

What was the aim of this Biomap research?
In the scoping review, the Biomap consortium identified 181 studies investigating biomarkers linked with more extensive psoriasis and/or other associated health conditions.


To read the lay summary and findings of this piece of research, click on the following link:
The search for measurable predictors linked with negative health complications in psoriasis.

If you need help or guidance about managing your psoriasis, contact the ISF Helpline here.